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Curriculum Vitae

 

Dr.rer.nat. Grit Bornschein (née Schaarschmidt)

University of Leipzig, Carl-Ludwig-Institute for Physiology, Dep. II

Liebigstraße 27, 04103 Leipzig, Germany

phone: (+49) 341 9715522

email: grit.bornschein@medizin.uni-leipzig.de

Room E201

 

Education & Scientific Career

 

since 2009        Research fellow, Carl-Ludwig-Institute for Physiology, University of Leipzig, Germany

2006 - 2009      PhD thesis; Department of Neurology, University of Leipzig, Germany

2006                  License to practice pharmacy (Approbation)

2004 – 2005    Diploma in pharmacy; Institute for Applied Dermatopharmacy, Martin-Luther-University Halle-Wittenberg, Germany

2000 – 2004     Studies of pharmacy; Martin-Luther-University, Halle-Wittenberg, Germany

 

Publications

 

Paul MM, Dannhäuser S, Morris L, Mrestani A, Hübsch M, Gehring J, Hatzopoulos GN, Pauli M, Auger GM, Bornschein G, Scholz N, Ljaschenko D, Müller M, Sauer M, Schmidt H, Kittel RJ, DiAntonio A, Vakonakis I, Heckmann M, Langenhan T

The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release.

Brain 2022; 145(11): 3787-3802

 

Bornschein G, Eilers J, Schmidt H

Neocortical high probability release sites are formed by distinct Ca²⁺ channel to release sensor topographies during development.

Cell Rep 2019; 28(6): 1410-1418 e1414.

 

Bornschein G, Schmidt H

Synaptotagmin Ca²⁺ sensors and their spatial coupling to presynaptic Ca_v channels in central cortical synapses.

Front Mol Neurosci 2018; 11: 494-510

 

Kusch V*, Bornschein G*, Loreth D, Bank J, Jordan J, Baur D, Watanabe M, Kulik A, Heckmann M, Eilers J, Schmidt H (*equally contributed)

Munc13-3 is required for the developmental localization of Ca2+ channels to active zones and the nanopositioning of Cav2.1 near release sensors.

Cell Reports 2018 ; 22, 1965-1973

 

Baur D, Bornschein G, Althof D, Watanabe M, Kulik A, Eilers J, Schmidt H

Developmental tightening of cerebellar cortical synaptic influx-release coupling.

J Neurosci 2015; 35(5): 1858-1871.

 

Bornschein G, Arendt O, Hallermann S, Brachtendorf S, Eilers J, Schmidt H.

Paired-pulse facilitation at recurrent Purkinje neuron synapses is independent of calbindin and parvalbumin during high-frequency activation.

J Physiol 2013 ; 591 (Pt 13): 3355-3370.

 

Winkler U, Hirrlinger PG, Sestu M, Wilhelm F, Besser S, Zemljic-Harpf AE, Ross RS, Bornschein G, Krügel U, Ziegler WH, Hirrlinger J.

Deletion of the cell adhesion adaptor protein vinculin disturbs the localization of GFAP in Bergmann glial cells.

Glia 2013; 61 (7): 1067-1083

 

Schmidt H, Brachtendorf S, Arendt O, Hallermann S, Ishiyama S, Bornschein G, Gall D, Schiffmann SN, Heckmann M, Eilers J

Nanodomain coupling at a cortical excitatory synapse.

Curr Biol 2013; 23(3): 244-249

 

Wegner F, Kraft R, Busse K, Schaarschmidt G, Härtig W, Schwarz SC, Schwarz J.

Glutamate receptor properties of human mesencephalic neural progenitor cells: NMDA enhances dopaminergic neurogenesis in vitro.

J Neurochem 2009; 111 (1): 204-216.

 

Schaarschmidt G, Wegner F, Schwarz SC, Schmidt H, Schwarz J.

Characterization of voltage-gated potassium channels in human neural progenitor cells.

PLoS ONE 2009; 4 (7) : e6168.

 

Schaarschmidt G*, Schewtschik S*, Kraft R, Wegner F, Eilers J, Schwarz J, Schmidt H. (*equally contributed)

A new culturing strategy optimizes functional neuronal development of human neural precursor cells.

J Neurochem 2009; 109 (1): 238-47.

 

Wegner F, Kraft R, Busse K, Härtig W, Schaarschmidt G, Schwarz J, Eilers J, Hevers W.

Functional analysis of GABA_A receptors in human midbrain-derived neural precursor cells.

J Neurochem 2008; 107 (4): 1056-1069.

 

Rzepka K, Schaarschmidt G, Nagler M, Wohlrab J.

Epidermal stem cells. J Dtsch Dermatol Ges 2005; 3 (12): 962-73.