Department I Hallermann » People » Torsten Bullmann


Dr. rer. nat. Torsten Bullmann

Carl-Ludwig-Institute for Physiology

University Leipzig, Liebigstr. 27, 04103 Leipzig, Germany

Room E 107

phone: +49 (0) 341 97 15327




Dr. Torsten Bullmann studied biology at the University of Leipzig, Germany. He received his diploma in biology in 2001 and his doctoral degree with summa cum laude in 2009, both from University of Leipzig. During his post-doc he worked for more than 7 year in Japan: at the RIKEN Center for Developmental Biology, at the RIKEN Quantitative Biology Center and at the Department for Informatics at the Kyoto university. In 2017 he returned to Germany to work as a full time lecturer for bioinformatics at the University for Applied Sciences Mittweida where he was tenured in 2018. He teached bachelor and master courses on bioinformatics, biological databases, programming, systems biology and modelling.

In 2019 he returned to Leipzig university to continue his studies on the role of microtubule associated protein tau in the regulation of neuronal activity during hibernation. His research interests include basic neuroscience, systems biology and application of machine learning. Currently he is using machine learning for the dense reconstruction of neuronal tissue from series of electron microscopy images as well as CMOS-based high density microelectrode arrays recordings of neuronal activity at different spatio-temporal scales. He is maintaining active collaborations with Kyoto university and ETH Zurich. During his free time he is enjoying kayaking and playing volleyball.

Curriculum Vitae

Education and training

2002-2010 PhD in Natural Sciences, Department for Neuroanatomy (Professor Dr. Thomas Arendt), Paul Flechsig Institute of Brain Research, Leipzig University, Leipzig, Germany
1994-2000 Diploma in Biology, Behavioral Physiology (Prof. Dr. Klaus Schildberger), Leipzig University, Leipzig, Germany

Scientific career

Since 2019 Research fellow, Department I (Prof. Dr. Stefan Hallermann), Carl-Ludwig-Institute for Physiology, Leipzig University, Leipzig, Germany
2017-2019 Lecturer (tenured), Bioinformatics (Prof. Dr. Dirk Labudde), University of Applied Sciences Mittweida, Mittweida, Germany
2017 Project Assistant Professor (Educational staff), Integrated Systems Biology Laboratory (Professor Dr. Shin Ishii), Graduate School of Informatics, Kyoto University, Kyoto, Japan
2016-2017 Researcher, Integrated Systems Biology Laboratory (Professor Dr. Shin Ishii), Graduate School of Informatics, Kyoto University, Kyoto, Japan
2014-2016 Senior Research Scientist, Frey Initiative Research Unit (Dr. Urs Frey), RIKEN Quantitative Biology Center, Kobe, Japan
2010-2014 Post Doc, Laboratory for Neocortical Development (Dr. Carina Hanashima), RIKEN Center for Developmental Biology, Kobe, Japan
2002-2010 Research Assistant/PhD student, Department for Neuroanatomy (Professor Dr. Thomas Arendt), Paul Flechsig Institute of Brain Research, Leipzig University, Leipzig, Germany
2001 Research Associate, Laboratory for Circadian Neurobiology (Professor Dr. Christopher S. Colwell), University of California Los Angeles (UCLA)
2001-2002 Research Assistant, Behavioral Physiology (Prof. Dr. Klaus Schildberger), Leipzig University, Leipzig, Germany


2011-2014 Foreign Post-doctoral Researcher grant (3 years; RIKEN, Japan)
2010-2011 Post-doctoral Scholarship (1 year; JSPS, Japan)


    • Reviewer for scientific journals, e.g., Nature Communications, Journal of Affective Disorders, Computer Methods and Programs in Biomedicine, eNeuro, Neuroscience, Journal of Comparative Neurology, Biochimica et Biophysica Acta (BBA) - General Subjects
    • Session chair for "OS 11, Neuroscience 3" at Europhysiology 2022, Kopenhagen, together with Prof. Dr. Andreas Draguhn


Pubmed →

Scholar →

    • Bullmann T*, Kaas T*, Ritzau-Jost A*, Woehner A, Kirmann T, Rizalar FS, Holzer M, Nerlich J, Geis C, Eilers J-K, Kittel RJ, Arendt T, Haucke V, Hallermann S (2024)
      Human iPSC-derived neurons have large presynaptic action potentials.
      The Journal of Neuroscience: The Official Journal of the Society for Neuroscience. (epub ahead of print) doi: 10.1523/jneurosci.0971-23.2024
      (*equal contribution)
    • Rizalar FS, Lucht MT, Petzoldt A, Kong S, Sun J, Vines JH, Telugu NS, Diecke S, Kaas T, Bullmann T, Schmied C, Löwe D, King JS, Cho W, Hallermann S, Puchkov D, Sigrist SJ, Haucke V.
      Phosphatidylinositol 3,5-bisphosphate facilitates axonal vesicle transport and presynapse assembly.
      Science. 2023 Oct 13;382(6667):223-230. doi: 10.1126/science.adg1075.
    • Steinke S, Kirmann T, Loi EA, Nerlich J, Weichard I, Kuhn P, Bullmann T, Ritzau-Jost A, Rizalar FS, Prüss H, Haucke V, Geis C, Hust M, Hallermann S.
      NMDA-receptor-Fc-fusion constructs neutralize anti-NMDA receptor antibodies.
      Brain. 2023 May 2;146(5):1812-1820. doi: 10.1093/brain/awac497.
    • Hörning M, Bullmann T, Shibata T.
      Local Membrane Curvature Pins and Guides Excitable Membrane Waves in Chemotactic and Macropinocytic Cells - Biomedical Insights From an Innovative Simple Model.
      Front Cell Dev Biol. 2021 Sep 15;9:670943. doi: 10.3389/fcell.2021.670943.
    • Urakubo H, Bullmann T, Kubota Y, Oba S, Ishii S.
      UNI-EM: An Environment for Deep Neural Network-Based Automated Segmentation of Neuronal Electron Microscopic Images.
      Sci Rep. 2019 Dec 19;9(1):19413. doi: 10.1038/s41598-019-55431-0.
    • Bullmann T, Radivojevic M, Huber ST, Deligkaris K, Hierlemann A, Frey U.
      Large-Scale Mapping of Axonal Arbors Using High-Density Microelectrode Arrays.
      Front Cell Neurosci. 2019 Sep 6;13:404. doi: 10.3389/fncel.2019.00404. eCollection 2019. PubMed PMID: 31555099; PubMed Central PMCID: PMC6742744.
    • Bullmann T, Feneberg E, Kretzschmann TP, Ogunlade V, Holzer M, Arendt T.
      Hibernation Impairs Odor Discrimination - Implications for Alzheimer's Disease.
      Front Neuroanat. 2019 Jul 16;13:69. doi: 10.3389/fnana.2019.00069. eCollection 2019. PubMed PMID: 31379517; PubMed Central PMCID: PMC6646461.
    • Deligkaris K, Bullmann T, Frey U.
      Extracellularly Recorded Somatic and Neuritic Signal Shapes and Classification Algorithms for High-Density Microelectrode Array Electrophysiology.
      Front Neurosci. 2016 Sep 14;10:421. doi: 10.3389/fnins.2016.00421. eCollection 2016. PubMed PMID: 27683541; PubMed Central PMCID: PMC5021702.
    • Bullmann T, Seeger G, Stieler J, Hanics J, Reimann K, Kretzschmann TP, Hilbrich I, Holzer M, Alpár A, Arendt T.
      Tau phosphorylation-associated spine regression does not impair hippocampal-dependent memory in hibernating golden hamsters.
      Hippocampus. 2016 Mar;26(3):301-18. doi: 10.1002/hipo.22522. Epub 2015 Oct 13. PubMed PMID: 26332578.
    • Bullmann T, Arendt T, Frey U, Hanashima C.
      A transportable, inexpensive electroporator for in utero electroporation.
      Dev Growth Differ. 2015 Jun;57(5):369-377. doi: 10.1111/dgd.12216. Epub 2015 May 19. PubMed PMID: 25988525.
    • Obien ME, Deligkaris K, Bullmann T, Bakkum DJ, Frey U.
      Revealing neuronal function through microelectrode array recordings.
      Front Neurosci. 2015 Jan 6;8:423. doi: 10.3389/fnins.2014.00423. eCollection 2014. Review. PubMed PMID: 25610364; PubMed Central PMCID: PMC4285113.
    • Arendt T, Bullmann T.
      Neuronal plasticity in hibernation and the proposed role of the microtubule-associated protein tau as a "master switch" regulating synaptic gain in neuronal networks.
      Am J Physiol Regul Integr Comp Physiol. 2013 Sep;305(5):R478-89. doi: 10.1152/ajpregu.00117.2013. Epub 2013 Jul 3. Review. PubMed PMID: 23824962.
    • Stieler JT, Bullmann T, Kohl F, Tøien Ø, Brückner MK, Härtig W, Barnes BM, Arendt T.
      The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation.
      PLoS One. 2011 Jan 18;6(1):e14530. doi: 10.1371/journal.pone.0014530. PubMed PMID: 21267079; PubMed Central PMCID: PMC3022585.
    • Bullmann T, Härtig W, Holzer M, Arendt T.
      Expression of the embryonal isoform (0N/3R) of the microtubule-associated protein tau in the adult rat central nervous system.
      J Comp Neurol. 2010 Jul 1;518(13):2538-53. doi: 10.1002/cne.22351. PubMed PMID: 20503426.
    • Bullmann T, Holzer M, Mori H, Arendt T.
      Pattern of tau isoforms expression during development in vivo.
      Int J Dev Neurosci. 2009 Oct;27(6):591-7. doi: 10.1016/j.ijdevneu.2009.06.001. Epub 2009 Jun 18. PubMed PMID: 19540327.
    • Stieler JT, Bullmann T, Kohl F, Barnes BM, Arendt T.
      PHF-like tau phosphorylation in mammalian hibernation is not associated with p25-formation.
      J Neural Transm (Vienna). 2009 Mar;116(3):345-50. doi: 10.1007/s00702-008-0181-x. Epub 2009 Jan 28. PubMed PMID: 19184336.
    • Härtig W, Stieler J, Boerema AS, Wolf J, Schmidt U, Weissfuss J, Bullmann T, Strijkstra AM, Arendt T.
      Hibernation model of tau phosphorylation in hamsters: selective vulnerability of cholinergic basal forebrain neurons - implications for Alzheimer's disease.
      Eur J Neurosci. 2007 Jan;25(1):69-80. PubMed PMID: 17241268.
    • Bullmann T, de Silva R, Holzer M, Mori H, Arendt T.
      Expression of embryonic tau protein isoforms persist during adult neurogenesis in the hippocampus.
      Hippocampus. 2007;17(2):98-102. PubMed PMID: 17183532.