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Baeza-Lehnert F, Flores CA, Guequén A, Barros LF.
Monitoring Lactate Dynamics in Individual Macrophages with a Genetically Encoded Probe.
Methods Mol Biol. 2020;2184:19-30. doi: 10.1007/978-1-0716-0802-9_2.
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Barros LF, San Martín A, Ruminot I, Sandoval PY, Baeza-Lehnert F, Arce-Molina R, Rauseo D, Contreras-Baeza Y, Galaz A, Valdivia S.
Fluid Brain Glycolysis: Limits, Speed, Location, Moonlighting, and the Fates of Glycogen and Lactate.
Neurochem Res. 2020 Jun;45(6):1328-1334. doi: 10.1007/s11064-020-03005-2. Epub 2020 Mar 6.
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Barros LF, Ruminot I, San Martín A, Lerchundi R, Fernández-Moncada I, Baeza-Lehnert F.
Aerobic Glycolysis in the Brain: Warburg and Crabtree Contra Pasteur.
Neurochem Res. 2020 Jan 24. doi: 10.1007/s11064-020-02964-w. Online ahead of print.
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Contreras-Baeza Y, Sandoval PY, Alarcón R, Galaz A, Cortés-Molina F, Alegría K, Baeza-Lehnert F, Arce-Molina R, Guequén A, Flores CA, San Martín A, Barros LF.
Monocarboxylate transporter 4 (MCT4) is a high affinity transporter capable of exporting lactate in high-lactate microenvironments.
J Biol Chem. 2019 Dec 27;294(52):20135-20147. doi: 10.1074/jbc.RA119.009093. Epub 2019 Nov 12.
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Barros LF, Baeza-Lehnert F.
Perfect energy stability in neurons. Aging (Albany NY).
2019 Sep 9;11(17):6622-6623. doi: 10.18632/aging.102257. Epub 2019 Sep 9.PMID: 31503004
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Baeza-Lehnert F, Saab AS, Gutiérrez R, Larenas V, Díaz E, Horn M, Vargas M, Hösli L, Stobart J, Hirrlinger J, Weber B, Barros LF.
Non-Canonical Control of Neuronal Energy Status by the Na(+) Pump.
Cell Metab. 2019 Mar 5;29(3):668-680.e4. doi: 10.1016/j.cmet.2018.11.005. Epub 2018 Dec 6. PubMed PMID: 30527744.
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Barros LF, San Martín A, Ruminot I, Sandoval PY, Fernández-Moncada I, Baeza-Lehnert F, Arce-Molina R, Contreras-Baeza Y, Cortés-Molina F, Galaz A,Alegría K.
Near-critical GLUT1 and Neurodegeneration.
J Neurosci Res. 2017 Nov;95(11):2267-2274. doi: 10.1002/jnr.23998. Epub 2017 Feb 2. Review. PubMed PMID: 28150866.
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Mächler P, Wyss MT, Elsayed M, Stobart J, Gutierrez R, von Faber-Castell A, Kaelin V, Zuend M, San Martín A, Romero-Gómez I, Baeza-Lehnert F, Lengacher S, Schneider BL, Aebischer P, Magistretti PJ, Barros LF, Weber B.
In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons.
Cell Metab. 2016 Jan 12;23(1):94-102. doi: 10.1016/j.cmet.2015.10.010. Epub 2015 Nov 19. PubMed PMID: 26698914.
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Lerchundi R, Fernández-Moncada I, Contreras-Baeza Y, Sotelo-Hitschfeld T, Mächler P, Wyss MT, Stobart J, Baeza-Lehnert F, Alegría K, Weber B, Barros LF.
NH4(+) triggers the release of astrocytic lactate via mitochondrial pyruvate shunting.
Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11090-5. doi: 10.1073/pnas.1508259112. Epub 2015 Aug 18. PubMed PMID: 26286989; PubMed Central PMCID: PMC4568276.
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San Martín A, Sotelo-Hitschfeld T, Lerchundi R, Fernández-Moncada I, Ceballo S, Valdebenito R, Baeza-Lehnert F, Alegría K, Contreras-Baeza Y, Garrido-Gerter P, Romero-Gómez I, Barros LF.
Single-cell imaging tools for brain energy metabolism: a review.
Neurophotonics. 2014 Jul;1(1):011004. doi: 10.1117/1.NPh.1.1.011004. Epub 2014 May 29. PubMed PMID: 26157964; PubMed Central PMCID: PMC4478754.
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San Martín A, Ceballo S, Baeza-Lehnert F, Lerchundi R, Valdebenito R, Contreras-Baeza Y, Alegría K, Barros LF.
Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate.
PLoS One. 2014 Jan 21;9(1):e85780. doi: 10.1371/journal.pone.0085780. eCollection 2014. PubMed PMID: 24465702; PubMed Central PMCID: PMC3897509.
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Barros LF, San Martín A, Sotelo-Hitschfeld T, Lerchundi R, Fernández-Moncada I, Ruminot I, Gutiérrez R, Valdebenito R, Ceballo S, Alegría K, Baeza-Lehnert F, Espinoza D.
Small is fast: astrocytic glucose and lactate metabolism at cellular resolution.
Front Cell Neurosci. 2013 Mar 22;7:27. doi: 10.3389/fncel.2013.00027. eCollection 2013. PubMed PMID: 23526722; PubMed Central PMCID: PMC3605549.