Department II Eilers » People » Robert Kraft

  

Dr. rer. nat. habil., Dipl.-Biophysiker

Carl-Ludwig-Institute for Physiology
Universität Leipzig, Liebigstr. 27, 04103 Leipzig, Germany
Room 206

phone: +49 (0) 341 97 15528
email: robert.kraft@medizin.uni-leipzig.de

Curriculum Vitae

1990–1995 Biophysics Studies, Humboldt University Berlin
1995 Diploma Degree in Biophysics (M.S. Equivalent), Humboldt University Berlin
1995–1996 Scientific Associate, Institute of Biophysics, Humboldt University Berlin
1996–2000 Scientific Associate, Institute of Pathology (Neuropathology), Friedrich Schiller University Jena
2001 Dr. rer. nat. (PhD) “Biophysics”, Faculty of Mathematics and Natural Sciences I, Humboldt University Berlin
2001–2004 Scientific Associate, Institute of Pharmacology,Free University Berlin / Charité Berlin
2005– Scientific Associate, Institute of Physiology (Neurophysiology), University Leipzig
2010 Dr. rer. nat. habil. “Physiology”, Medical Faculty, University Leipzig

Articles and book chapters

2012

  • Grabiec* U, Koch* M, Kallendrusch S, Kraft R, Hill K, Merkwitz C, Ghadban C, Straiker A, Dehghani F (2012)
    The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB1).
    Neuropharmacology
  • Ödemis V, Lipfert J, Kraft R, Hajek P, Abraham G, Hattermann K, Mentlein R, Engele J (2012)
    The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells.
    Glia
  • Günther C, Laube M, Liebert UG, Kraft R (2012)
    Differential regulation of voltage-gated Ca2+ currents and metabotropic glutamate receptor activity by measles virus infection in rat cortical neurons.
    Neurosci Lett 506:17-21.

2011

  • Kraft R (2011)
    Patch-Clamp-Technik.
    In: Molekulare Biotechnologie: Konzepte und Methoden, 2. Auflage. Wink (Ed.), Wiley-VCH, Weinheim, 185-189.
  • Kraft R (2011)
    Patch Clamp Method.
    In: An Introduction to Molecular Biotechnology, 2nd Edition. Wink (Ed.), Wiley-VCH, Weinheim, 177-181.

2010

  • Hoffmann* A, Grimm* C, Kraft R, Goldbaum O, Wrede A, Nolte C, Hanisch UK, Richter-Landsberg C, Brück W, Kettenmann H, Harteneck C (2010)
    TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes.
    J Neurochem 114:654-665.
  • Wehrhahn J, Kraft R, Harteneck C, Hauschildt S (2010)
    Transient receptor potential melastatin 2 is required for lipopolysaccharide-induced cytokine production in human monocytes.
    J Immunol 184:2386-2393.

2009

  • Berna-Erro* A, Braun* A, Kraft R, Kleinschnitz C, Schuhmann MK, Stegner D, Wultsch T, Eilers J, Meuth SG, Stoll G, Nieswandt B (2009)
    STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death.
    Sci Signalv2:ra67.
  • Wegner F, Kraft R, Busse K, Schaarschmidt G, Härtig W, Schwarz SC, Schwarz J (2009)
    Glutamate receptor properties of human mesencephalic neural progenitor cells: NMDA enhances dopaminergic neurogenesis in vitro.
    J Neurochem 111:204-216.
  • Schaarschmidt* G, Schewtschik* S, Kraft R, Wegner F, Eilers J, Schwarz J, Schmidt H (2009)
    A new culturing strategy improves functional neuronal development of human neural progenitor cells.
    J Neurochem 109:238-247.

2008

  • Wegner F, Kraft R, Busse K, Härtig W, Schaarschmidt G, Schwarz SC, Schwarz J, Hevers W (2008)
    Functional and molecular analysis of GABAA receptors in human midbrain-derived neural precursor cells.
    J Neurochem 107:1056-1069.

2007

  • Kraft R (2007)
    The Na+/Ca2+ exchange inhibitor KB-R7943 potently blocks TRPC channels.
    Biochem Biophys Res Commun 361:230-236.
  • Harteneck C, Frenzel H, Kraft R (2007)
    N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A2 inhibitor and TRP channel blocker.
    Cardiovasc Drug Rev 25:69-75.

2006

  • Reiter B, Kraft R, Günzel D, Fromm M, Zeissig S, Schulzke HJ, Harteneck C (2006)
    TRPV4-mediated regulation of epithelial permeability.
    FASEB J 20:1802-1812.
  • Kraft R, Grimm C, Frenzel H, Harteneck C (2006)
    Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid.
    Br J Pharmacol 148:264-273.
  • Kraft R, Patt S (2006)
    The Patch Clamp Method.
    In: An Introduction to Molecular Biotechnology. Ed. Wink, M., Wiley-VCH, Weinheim, 237-243.

2005

  • Grimm* C, Kraft* R, Schultz G, Harteneck C (2005)
    Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine.
    Mol Pharmacol 67:798-805.
  • Kraft R, Harteneck C (2005)
    The mammalian melastatin-related transient receptor potential cation channels: an overview.
    Pflügers Arch 451:204-211.

2004

  • Kraft R, Grimm C, Grosse K, Hoffmann A, Sauerbruch S, Kettenmann H, Schultz G, Harteneck C (2004)
    Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia.
    Am J Physiol Cell Physiol 286:C129-C137.
  • Patt S, Preussat K, Beetz C, Kraft R, Schrey M, Kalff R, Schönherr K, Heinemann SH (2004)
    Expression of ether á go-go potassium channels in human gliomas.
    Neurosci Lett 368:249-253.
  • Kraft R, Patt S (2004)
    Patch-Clamp-Technik.
    In: Molekulare Biotechnologie. Hrsg. Wink, M., Wiley-VCH, Weinheim, 247-254.

2003

  • Grimm* C, Kraft* R, Sauerbruch S, Schultz G, Harteneck C (2003)
    Molecular and functional characterization of the melastatin-related cation channel TRPM3.
    J Biol Chem 278:21493-21501.
  • Preussat K, Beetz C, Schrey M, Kraft R, Wölfl S, Kalff R, Patt S (2003)
    Expression of Kv1.3 and Kv1.5 potassium channels in human gliomas.
    Neurosci Lett 346:33-36.
  • Kraft R, Krause P, Jung S, Basrai D, Liebmann L, Bolz J, Patt S (2003)
    BK channel openers inhibit migration of human glioma cells.
    Pflügers Arch 446:248-255.

2002

  • Basrai D, Kraft R, Bollensdorff C, Liebmann L, Benndorf K, Patt S (2002)
    BK channel blockers inhibit potassium-induced proliferation of human astrocytoma cells.
    Neuroreport 13:403-407.
  • Schrey M, Codina C, Kraft R, Beetz C, Kalff R, Wölfl S, Patt S (2002)
    Molecular characterization of voltage-gated sodium channels in human gliomas.
    Neuroreport 13:2493-2498.

2001

  • Kraft R, Basrai D, Benndorf K, Patt S (2001)
    Serum deprivation and NGF induce and modulate voltage-gated Na+ currents in human astrocytoma cell lines.
    Glia 34:59-67.

2000

  • Kraft R, Benndorf K, Patt S (2000)
    Large conductance Ca2+-activated K+ channels in human meningioma cells.J Membr Biol 175:25-33.
  • Patt S, Steenbeck J, Hochstetter A, Kraft R, Huonker R, Haueisen R, Haberland N, Ebmeier K, Hliscs R, Fiehler J, Nowak H, Kalff R (2000)
    Source localization and possible causes of interictal epileptic activity in tumor-associated epilepsy.
    Neurobiol Dis 7:260-269.
  • Codina* C, Kraft* R, Pietsch T, Prinz M, Steinhäuser C, Cervós-NavarroJ, Patt S (2000)
    Voltage- and g-aminobutyric acid-activated membrane currents in the human medulloblastoma cell line MHH-MED-3.
    Neurosci Lett 287:53-56.
  • Kaufmann R, Patt S, Zieger M, Kraft R, Tausch S, Henklein P, Nowak G (2000)
    The two-receptor system PAR-1/PAR-4 mediates a-thrombin-induced [Ca2+]i mobilization in human astrocytoma cells.
    J Cancer Res Clin Oncol 126:91-94.

1999

  • Kaufmann R, Patt S, Zieger M, Kraft R, Nowak G (1999)
    Presence of the proteinase-activated receptor-2 (PAR-2) in human brain tumor cells - trypsin- and SLIGRL-induced calcium response in primary cultured meningiomas.
    Cancer Lett 139:109-113.
  • Kaufmann R, Patt S, Kraft R, Zieger M, Henklein P, Neupert G, Nowak G (1999)
    PAR 1-type thrombin receptors are involved in thrombin-induced calcium signaling in human meningioma cells.
    J Neurooncol 42:131-136.