DFG founded research groups » Research Group Schmidt » Publications

Publications

Research Paper

  • Bornschein, G., Eilers J. and Schmidt, H. (2019)
    Neocortical High Probability Release Sites are Formed by Distinct Ca2+ Channel to Release Sensor Topographies During Development.
    Cell Report, in press.
  • Bornschein, G., Eilers J. and Schmidt, H. (2019)
    Neocortical High Probability Release Sites are Formed by Distinct Ca2+ Channel to Release Sensor Topographies During Development.
  • Kusch, V., Bornschein, G., Loreth, D., Bank, J., Jordan, J., Baur, D., Watanabe, M., Kulik, A., Heckmann, M., Eilers, J., & Schmidt, H., 2018
    Munc13-3 is required for the developmental localization of Ca2+ channels to active zones and the nanopositioning of Cav2.1 near release sensors.
    Cell Reports 22, 1965-1973
  • Doussau F., Schmidt H., Dorgans K., Valera A. M., Poulain B. and Isope P., 2017
    Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity
    eLife 6:e28935 doi: 10.7554/eLife.28935
  • Mondragão M. A., Schmidt H., Kleinhans C., Langer J., Kafitz K. W. and Rose C. R., 2016
    Extrusion versus diffusion: mechanisms for recovery from sodium loads in mouse CA1 pyramidal neurons.
    J Physiol. 2016 doi: 10.1113/JP272431
  • Baur D., Bornschein G., Althof D., Watanabe M., Kulik A., Eilers J. and Schmidt H., 2015.
    Developmental tightening of cerebellar cortical synaptic influx-release coupling.
    J. Neurosci.35(5): 1858-1871.
  • Brachtendorf S., Eilers J. and Schmidt H., 2015.
    A use-dependent increase in release sites drives facilitation at calretinin-deficient cerebellar parallel-fiber synapses.
    Front Cell Neurosci 9: DOI 10.3389/fncel.2015.00027.
  • Ishiyama S., Schmidt H., Cooper B.H., Brose N. and Eilers J., 2014.
    Munc13-3 superprimes synaptic vesicles at granule cell-to-basket cell synapses in the mouse cerebellum.
    J Neurosci, 34(44): 14687-14696.
  • Mortensen L.S., Schmidt H., Farsi Z., Barrantes-Freer A., Rubio M.E., Ufartes R., Eilers J., Sakaba T., Stühmer W. and Pardo L.A., 2014.
    KV10.1 potassium channels modulate presynaptic short-term plasticity at the parallel fiber - Purkinje cell synapse.
    J Physiol (Lond), 4. DOI:10.1113/jphysiol.2014.281600.
  • Arendt O., Schwaller B., Brown E.B., Eilers J., Schmidt H, 2013
    Restricted diffusion of calretinin in cerebellar granule cell dendrites implies Ca2+-dependent interactions via its EF-hand 5 domain.
    J Physiol. 2013 Jun 3. [Epub ahead of print] IF 4.88.
  • Bornschein G., Arendt O., Hallermann S., Brachtendorf S., Eilers J. AND Schmidt H, 2013
    Paired-pulse facilitation at recurrent Purkinje neuron synapses is independent of calbindin and parvalbumin during high-frequency activation.
    J Physiol. 2013 Jul 1;591(Pt 13):3355-3370. Epub 2013 May 13.IF 4.88
  • Schmidt H, Brachtendorf S*, Arendt O, Hallermann S, Ishiyama S, Bornschein G, Gall D, Schiffmann SN, Heckmann M, Eilers J (2013)
    Nanodomain Coupling at an Excitatory Cortical Synapse.
    Curr Biol. 3, 244-249. IF 10.99
  • Schmidt H, Arendt O. and Eilers J. 2011.
    Diffusion and extrusion shape standing calcium gradients during ongoing parallel fiber activity in dendrites of Purkinje neurons.
    Cerebellum. 11(3):694-705. IF3.29
  • Hallermann S., Fetjova A., Schmidt H, Weyhersmüller A., Silver R.A., Gundelfinger E.D. and Eilers J. 2010.
    Bassoon speeds vesicle reloading at a central excitatory synapse.
    Neuron 68(4) 710-23. IF 14.67.
  • Guzman S.J., Schmidt H, Franke H., Krügel U., Eilers J. and Gerevich Z.., 2010.
    P2Y1 receptors inhibit long-term depression in the prefrontal cortex.
    Neuropharm. 59(6): 406-15.
  • Schaarschmidt G., Wegener, F., Schwarz, S.C., Schmidt H and Schwarz, J., 2009b.
    Characterization of voltage gated potassium channels in human neural progenitor cells.
    PLOS One. Jul 8;4(7):e6168.
  • Schaarschmidt G., Schewtschik S., Eilers J., Schwarz, J. and Schmidt H, 2009a.
    A new culturing strategy optimizes functional neuronal development of midbrain derived precursors.
    J Neurochem 109: 238-247. IF 4.451. Zitierungen 4.
  • Schmidt H, and Eilers J., 2009.
    Regulation of Ca2+ buffer mediated spino-dendritic cross-talk by the spine neck geometry.
    J Comput Neurosci 27(2):229-43.
  • Schmidt H, Arendt O., Brown E. B., Schwaller B., and Eilers J., 2007a.
    Parvalbumin is freely mobile in axons, somata and nuclei of cerebellar Purkinje neurons.
    J Neurochem 100: 727-735.
  • Schmidt H, Kuhnert S., Wilms C., Strotmann R. and Eilers J., 2007b.
    Spino-dendritic cross-talk mediated by mobile endogenous Ca2+ binding proteins.
    J Physiol (Lond.) 2: 619-629.
  • Wilms C., Schmidt H and Eilers J., 2006.
    Quantitative two-photon Ca2+ imaging via fluorescence lifetime analysis.
    Cell Calcium 40: 73-79.
  • Schmidt H, Schwaller B. and Eilers J., 2005.
    Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons.
    PNAS 102: 5850-5855.
  • Küppers-Munther B., Letzkus J.J., Lüer k., Technau G. M., Schmidt H and Prokop A., 2004.
    A new culturing strategy optimises Drosophila primary cell cultures for structural and functional analyses of synapses.
    DEV Biol 269(2):459-78.
    Diese Arbeit liegt der Erteilung des Patents über Zellkulturmedien zugrunde.
  • Schmidt H, Stiefel K. M., Racay P., Schwaller B. and Eilers J., 2003b.
    Mutational analysis of dendritic Ca2+ kinetics in cerebellar Purkinje cells: Role of parvalbumin and calbindin D28k.
    J Physiol (Lond.) 551: 13-32.
  • Schmidt H, Brown E. B., Schwaller B. and Eilers J., 2003a.
    Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching.
    Biophys J 84: 2599-2608.
  • Schmidt H., Lüer K., Hevers W. and Technau G. M., 2000.
    Ionic currents of Drosophila embryonic neurons derived from selectively cultured CNS midline precursors.
    J Neurobiol 44: 392-413.
  • Schmidt H., Rickert C., Bossing T., Vef O., Urban J. and Technau G. M., 1997.
    The embryonic central nervous system lineages of Drosophila melanogaster. II. Neuroblast lineages derived from the dorsal part of the neruoectoderm.
    Dev Biol 189: 186-204.

Review Article (Peer Review)

  • Schmidt H. (2019)
    Control of Presynaptic Parallel Fiber Efficacy by Activity Dependent Regulation of the Number of Occupied Release Sites.
    Front. Syst. Neurosci., in press.
  • Bornschein, G. and Schmidt, H. (2018)
    Synaptotagmin Ca2+ sensors and their spatial coupling to presynaptic Cav channels in central cortical synapses.
    Front. Mol. Neurosci. 11, 494. doi: 10.3389/fnmol.2018.00494.
  • Schmidt H. (2019)
    Control of Presynaptic Parallel Fiber Efficacy by Activity Dependent Regulation of the Number of Occupied Release Sites.
    Front. Syst. Neurosci.
  • Bornschein, G. and Schmidt, H. (2018)
    Synaptotagmin Ca2+ sensors and their spatial coupling to presynaptic Cav channels in central cortical synapses.
    Front. Mol. Neurosci. 11, 494. doi: 10.3389/fnmol.2018.00494.
  • Isope P., Wilms C. D. and Schmidt H., 2016
    Determinants of synaptic information transfer: From Ca2+ binding proteins to Ca2+ signaling domains.
    Front Cell Neurosci, 2016, DOI: 10.3389/fncel.2016.00069
  • Schmidt H 2012.
    Three functional facets of calbidin-28k.
    FRONT. MOL. NEUROSCI. 5: DOI10.3389/fnmol.2012.00025.

Book Chapter

  • Schmidt H., 2013.
    27. Calcium buffering: Models of Ca2+-dynamics and steady-state approximations.
    27. In: Encyclopedia of Computational Neuroscience. Eds: D. Jaeger, R. Jung. Springer Science+Business New York. DOI 10.1007/978-1-4614-7320-6_177-1.
  • Schmidt H and Eilers J., 2010.
    A practical guide: dye loading with patch pipettes.
    In: Imaging in neuroscience and development: a laboratory manual, (R. Yuste and A. Konnerth eds.), pp. Cold Spring Harbor Laboratory Press, New York.
  • Schmidt H and Eilers J., 2007c.
    Combined fluorometric and electrophysiological recordings.
    In: Patch-Clamp Analysis: Advanced techniques. Eds: Boulton A. A., Baker G. B., Waltz W., Humana Press Inc, Totowa, New Jersey.
  • Schmidt H and Eilers J., 2002.
    Combined fluorometric and electrophysiological recordings.
    In: Advanced techniques for patch-clamp analysis. Eds: Boulton A. A., Baker G. B., Waltz W., Humana Press Inc, Totowa, New Jersey.
  • Schmidt H., Isope, P., Wilms C (Editoren).
    Research Topic: Determinants of synaptic information transfer: From Ca2+ binding proteins to Ca2+ signalling domains.
    Frontiers in Cellular Neuroscience (IF 4.2).

Other Publications